I don't think it matters much one way or another for me. Sometimes I thought it'd be slightly easier for me personally to be male because I like work and don't like taking care of kids but then horrible male stereotypes just bring it back to a net neutral.
Also, I'm pretty sure you can change your sex by losing/gaining weight/muscle for all the people who put "yes" on the poll so if you feel like experimenting try it but be cautious.