This was the first TV drama series I fell in love with. Anthony Edwards as Dr. Mark Greene was my favorite character. When he left ER, I cried. Literally cried physical tears. I've never been so attached to a TV show since.

To give context to the second clip, you have to see the first clip from the pilot episode, season one. The head nurse tries to commit suicide by taking an overdose of pills, Dr. Greene manages the case which is looking dire. William H. Macy as Dr. Morgenstern tells Mark, "You set the tone." This becomes a "meme" throughout the show.