Yeah, a change indicates a loss, and a gain, lots of uncertainty. The loss is certain tho, the gain requires the loss to exist and doesn't seem granted, it's uncertain what will be gained. The "gain" may also be unwanted
As exemple, when one part of a couple wants to split up but not the other, they both gains their freedom to date back and the possibility to find someone better yet it doesn't necessarily feels like a gain, more like a burden, a bad fate.
The possibility of loss and gaining worse keeps many up at night.