What animes have LIE's as the protagonist?

[The Reality Denialist]

I have a hard time telling apart LIE inventors from ILEs

Esay: LIE's are seeking for science in utilization perspective. ILE's just do it for discovery. I think seeing science as a tool to get something out of it seems like a blasphemy at first glance but it helps to discover new things.

[Averroes]

I have a hard time telling apart LIE inventors from ILEs, like Senku, or Mei Hatsume.

You get this vibe from them that they're very focused on "building their brand" but I don't know if that's enough.

Senku’s followers seem like serious types (SEE or IEE for Chrome, ESI for Kohaku, LSE for Taiju)

[totalize]

I think Rock in Black Lagoon might be LIE, could also be ILI though.

[mclane]

Kintaro Oe, the protagonist of Golden Boy, is probably a LIE-Ni. It's a comedy series, but it's the only instance I can think of. LIE's are underrepresented in anime and media.

[Averroes]

Bruno Bucciariti - Ni-LIE or LSI