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Thread: Model D

  1. #761
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    openness to change logical reasoning (dlPFC, vlPFC) <--> Ti, Te

    episodic simulation (vmPFC) <--> Ni

    memory retrieval, intuition (dmPFC) <--> Ne
    Last edited by Petter; 11-29-2022 at 03:37 PM.

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    https://en.wikipedia.org/wiki/Cognit..._underpinnings

    "Activation of the dorsolateral PFC has been shown during resolution of interference of irrelevant task sets."

    "Activation is mediated by the level of abstractness of the set switch in an anterior to posterior fashion within the PFC, with the most anterior activations elicited by set switches and the most posterior activations resulting from stimulus or perceptual switches."

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    https://en.wikipedia.org/wiki/Prefrontal_synthesis

    "The mechanism of PFS is hypothesized to involve synchronization of several independent object-encoding neuronal ensembles (objectNEs). When objectNEs fire out-of-sync, the objects are perceived one at a time. However, once those objectNEs are time-shifted by the lateral prefrontal cortex (LPFC) to fire in-phase with each other, they are consciously experienced as one unified object or scene."

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    openness to change dlPFC and vlPFC <--> creativity
    Last edited by Petter; 11-29-2022 at 03:42 PM.

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    memory retrieval, intuition (dmPFC) <--> Ne
    ... and thinking outside the box

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    The striatum receives inputs from multiple cortical regions (Webster, 1961; Beckstead, 1979; Hintiryan et al., 2016; Hunnicutt et al., 2016), and prefrontal inputs to the striatum have been shown to play significant roles in both goal-directed, as well as habitual behavior (Gourley and Taylor, 2016; Smith and Laiks, 2017; Amaya and Smith, 2018). The major frontal structures that have been implicated in instrumental and automatic behaviors are the prelimbic cortex (PL) and infralimbic cortex (IL) Amaya and Smith, 2018 in the medial prefrontal cortex (mPFC), as well as the OFC located in the ventral part of the PFC.

    Interestingly, the two substructures of the mPFC, the IL and PL, seem to play opposing roles in balancing between goal and habit, with the IL supporting habitual behavior, and the PL supporting goal-directed behavior (Smith and Laiks, 2017; Amaya and Smith, 2018).

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    8. openness to change vs. habitual behavior (PFC mPFC vs. the striatum ... or the prelimbic cortex (PL) vs. the infralimbic cortex (IL))

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    https://www.frontiersin.org/articles...014.00235/full

    The prelimbic (PL) cortex allows rodents to adapt their responding under changing experimental circumstances. In line with this, the PL cortex has been implicated in strategy set shifting, attentional set shifting, the resolution of response conflict, and the modulation of attention towards predictive stimuli.

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    12. cognitive control, attention, working memory (PFC: high activity vs. low activity)

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    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708542/ (Neural structures underlying set-shifting: roles of medial prefrontal cortex and anterior cingulate cortex)

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    13. (?) many connections between dmPFC and the rest of the brain (intuition or thinking outside the box) vs. few connections between dmPFC and the rest of the brain

    dmPFC: see page 12

    brain22.png

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    https://www.frontiersin.org/articles...22.999320/full

    However, the dmPFC has been strongly implicated in multiple aspects of behavioral flexibility including set-shifting (Ragozzino et al., 1999; Stefani et al., 2003; Floresco et al., 2006, 2008; Bissonette and Roesch, 2015; Powell and Redish, 2016; Brockett et al., 2020) and response inhibition (Bussey et al., 1996; Muir et al., 1996; Narayanan and Laubach, 2006; Jonkman et al., 2009; Terra et al., 2020; Hamel et al., 2022). Such studies have revealed that the dmPFC is important for withholding or otherwise modifying learned motor behaviors (e.g., instrumental habits), but do not directly address its role in negatively regulating Pavlovian incentive motivation as measured by PIT.

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    8. <--> 13.

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    brain40.png

    anterior dmPFC <--> DMN

    posterior dmPFC <--> FPN (or CEN)

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    https://scholar.harvard.edu/files/na...w_ni_2009b.pdf

    "... demonstrated greater activity in both cognitive/evaluative (posterior dmPFC) and emotional/interoceptive (anterior dmPFC) cortical regions."

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    https://pubmed.ncbi.nlm.nih.gov/28054822/

    "the ventromedial prefrontal cortex (vmPFC) is implicated in episodic future thinking (EFT)"

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