Esay: LIE's are seeking for science in utilization perspective. ILE's just do it for discovery. I think seeing science as a tool to get something out of it seems like a blasphemy at first glance but it helps to discover new things.
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Senku’s followers seem like serious types (SEE or IEE for Chrome, ESI for Kohaku, LSE for Taiju)
https://www.youtube.com/watch?v=lwfnhRLQXko
https://www.youtube.com/watch?v=7VoMcCeeLp4
I think Rock in Black Lagoon might be LIE, could also be ILI though.
Kintaro Oe, the protagonist of Golden Boy, is probably a LIE-Ni. It's a comedy series, but it's the only instance I can think of. LIE's are underrepresented in anime and media.
Bruno Bucciariti - Ni-LIE or LSI
https://www.youtube.com/watch?v=g4NL8y5T3GQ
https://www.youtube.com/watch?v=TSZ8dBHS67U