inb4 most thread in existence.
I think a key aspect to is avoiding losing intellectual freedom. For instance, when it comes to looking at various religious, spiritual or ethical systems, sees the raw materials for constructing its own beliefs, rather than systems that must be committed too. This is the "passive" aspect of seeking.
"Active" seeking would be, personally, the point at which I realised that I can't look at a thing and appraise its full potential unless I have a large bank of knowledge about stuff. You only get new ideas by adapting old ones; so information-seeking becomes an imperative.
Back to the title, my question is thus: when did you have that moment where you realised you wanted or needed to start learning more about the world for some end?